Difference between revisions of "BIONEXX"

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== Madagascar: producing the active ingredient for the world's only WHO approved malaria drug ==
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''Madagascar: producing the active ingredient for the world's only WHO approved anti-malaria drug''
  
=== Short description ===
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'''Malaria kills more than 400,000 people every year. 90% of these people live in Africa and by far the most of them are children under the age of five. According to UNICEF, malaria accounts for about one in six of all childhood deaths in Africa.'''
  
'''Malaria kills more than 400,000 people every year. 90% of these people live in Africa and by far the most of them are children under the age of five. According to UNICEF malaria accounts for about one in six of all childhood deaths in Africa.'''
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[[File:Bionexx_010.jpg|600px]]
  
In 1971, after reviewing 2000 candidate recipes, ancient texts, and folk remedies, the Chinese pharmaceutical chemist Tu Youyou discovered the Malaria curing power of a plant called ''Artemisia annua''. It took till 2004 for her invention to be translated into the market entry of an approved medicine. For her discovery, Tu received the Nobel Prize in 2015. Today, the so-called Artemisinin Combined Therapies (ACTs) are the only malaria curing medicines that are approved by the WHO.
+
In 1971, after reviewing 2,000 candidate recipes, ancient texts, and folk remedies, the Chinese pharmaceutical chemist Tu Youyou discovered the Malaria curing power of a plant named ''[[Artemisia annua]]''. It took until 2004 for her invention to enter the market as an approved medicine. Tu received the Nobel Prize in 2015 for her discovery. Today, the so-called Artemisinin Combined Therapies (ACTs) are the only malaria curing medicines that are approved by the World Health Organisation (WHO).
  
Other medicines exist, but have lost their effectiveness as the virus has developed a resistance against them. The only African country which produces ''Artemisia annua'' at scale is Madagascar. This is directly linked to the activities of Bionexx. ''Artemisia annua'' is typically grown by smallholder farmers. Due to its specific growing and harvesting conditions, it can be cultivated in the low season as a counter-crop of rice.
+
Other medicines exist, but have lost their effectiveness as the virus has developed a resistance against them. The only African country which produces ''Artemisia annua'' at a large scale is Madagascar. This is directly linked to the activities of Bionexx. ''Artemisia annua'' is typically grown by smallholder farmers. Due to its specific growing and harvesting conditions, it can be cultivated in the low season as a counter-crop of rice.
 
 
For the farmers, this cash crop is an interesting enhancement of their income per hectare. In Madagascar, around 10.000 farmers are supplying to Bionexx and derive about 25% from their annual cash revenue from this.
 
  
 
{| class="imageTable"
 
{| class="imageTable"
 
|-
 
|-
|colspan="3" | [[File:Bionexx_001.jpg|600px]]
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|colspan="3" | [[File:Bionexx_009.jpg|600px]]
 
|-
 
|-
|[[File:Bionexx_005.jpg|196px]]
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|[[File:Bionexx_007.jpg|196px]]
|align="center"|[[File:Bionexx_003.jpg|196px]]
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|align="center"|[[File:Bionexx_008.jpg|196px]]
|align="right"|[[File:Bionexx_004.jpg|196px]]
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|align="right"|[[File:Bionexx_012.jpg|196px]]
 
|}
 
|}
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For the farmers, ''Artemisia annua'' offers a new and interesting type of cash crop. Around 10,000 farmers supply Bionexx in Madagascar and derive about 25% of their annual cash revenue from growing ''Artemisia annua''.
  
 
=== Bionexx Madagascar ===
 
=== Bionexx Madagascar ===
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* is a semi-pharmaceutical company active in the identification, development and production of functional ingredients derived from plants, for use in the pharmaceutical, food and personal care industries.
 
* is a semi-pharmaceutical company active in the identification, development and production of functional ingredients derived from plants, for use in the pharmaceutical, food and personal care industries.
* $ 6.8 million turnover in 2016, of which 80% comes from Artemisinin.
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* had a $ 6.8 million turnover in 2016, of which 80% comes from Artemisinin.
 
* has successfully passed the most stringent quality audits of various pharma companies;
 
* has successfully passed the most stringent quality audits of various pharma companies;
 
* is now one of the leading Artemisinin suppliers globally, and the only based in Africa;
 
* is now one of the leading Artemisinin suppliers globally, and the only based in Africa;
* has installed capacity to strongly increase Artemisinin volume in the coming years.
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* has installed capacity to strongly increase Artemisinin volume in the coming years.<br><br>
 +
 
 +
{| class="imageTable"
 +
|-
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|colspan="3" | [[File:Bionexx_001.jpg|600px]]
 +
|-
 +
|[[File:Bionexx_004.jpg|196px]]
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|align="center"|[[File:Bionexx_005.jpg|196px]]
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|align="right"|[[File:Bionexx_003.jpg|196px]]
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|}
  
 
=== Strategy ===
 
=== Strategy ===
  
The strategy of Bionexx is centered around the following pillars:<br>
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The strategy of Bionexx is based upon:<br>
1. increasing production and sales volume of Artemisinin,<br>
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* increasing production and sales volume of Artemisinin.<br>
2. increasing the biomass supply through growing the supplier base of farmers growing ''Artemisia annua'' and to enhance their production per hectare in a sustainable manner.<br>
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* increasing the biomass supply through more farmers growing ''Artemisia annua'' and to enhance their production per hectare in a sustainable manner.<br>
3. diversification into other products based on botanical extracts.
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* diversification into other products derived on botanical extracts.<br><br>
 +
 
 +
[[File:Bionexx_011.jpg|600px]]
  
 
=== Partnerships ===
 
=== Partnerships ===
  
We have several existing partnerships focused on research (e. g. with universities and industrial partners), projects (e. g. local companies and organizations) and the development of activities (local and international companies).
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Bionexx has several existing partnerships focused on research (e. g. with universities and industrial partners), projects (e. g. local companies and organisations) and the development of activities (local and international companies).
  
We are open to discuss new opportunities to work together.
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Bionexx is open to discuss new opportunities and partnerships with individuals and organisations interested in the field of curing Malaria.
  
 
[[File:Bionexx_006.jpg]]
 
[[File:Bionexx_006.jpg]]
  
  
== Short contribution by Martin Gertz ==
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----
 +
 
 +
== Short contribution by Martin Gertz (August 2017) ==
  
Bionexx was founded 12 years ago with the idea of cultivating the plant ''[[Artemisia annua]]''. This was followed in 2007 by the acquisition of an existing factory for plant extraction in [[Fianarantsoa]], the testing of cultivation technology and cooperation with the farmers as well as the expansion of capacities and abilities for the extraction. In the second phase, the focus is now mainly on the increase in production. We have already made good progress which is reflected in the biomass production (1,500 tons), the number of farmers (about 10,000) and the number of employees (450). There are also a few other projects which have been launched in parallel and partly with partners (e.g. joint ventures for the extraction of quinine from tree bark) and which are supposed to shape the 3rd phase in the development of Bionexx.
+
Bionexx was founded 12 years ago with the idea of cultivating the plant ''[[Artemisia annua]]''. This was followed in 2007 by the acquisition of an existing factory for plant extraction in [[Fianarantsoa]], the testing of cultivation technology and cooperation with the farmers as well as the expansion of capacities and abilities for the extraction. Now in the second phase, the focus is mainly on the increase of production. We have already made good progress which is reflected in the biomass production (1,500 tons), the number of farmers (about 10,000) and the number of employees (450). There are also a few other projects which have been launched in parallel and partly with partners (e.g. joint ventures for the extraction of quinine from tree bark) and which are supposed to shape the 3rd phase in the development of Bionexx.
  
As Corporate Finance Manager it is my task to find more partners. Our focus is on "impact" oriented partners who support the approach and the strategic perspective of Bionexx. We are open to cooperation with institutional (funds, foundations) as well as strategic or private investors.
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As Corporate Finance Manager, one of my tasks is to find more partners. Our focus is on impact-oriented partners who support the approach and the strategic perspective of Bionexx. We are open to cooperation with institutional (funds, foundations) as well as strategic or private investors.
  
 
In the future, we will also seek further project or activity related partnerships with local or international companies and institutions.
 
In the future, we will also seek further project or activity related partnerships with local or international companies and institutions.
  
Please contact me if you are interested or know someone who is interested in a partnership.
+
Please contact me if you are interested or know someone who is interested in a partnership with Bionexx.
  
 
'''Martin Gertz'''<br>
 
'''Martin Gertz'''<br>
Corporate Finance Manager<br>
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Corporate Finance Manager
Bionexx S.A.
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 +
Bionexx S.A.<br>
 +
Tana Waterfront (Injet building, 2nd floor)<br>
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Ambodivona<br>
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BP 8707<br>
 +
101 - Antananarivo<br>
 +
Madagascar
  
 
Website: [http://www.bionexx.com www.bionexx.com]<br>
 
Website: [http://www.bionexx.com www.bionexx.com]<br>
 
Tel: +261 (0)32 03 023 21<br>
 
Tel: +261 (0)32 03 023 21<br>
 
Email: [mailto:mgertz@bionexx.com mgertz@bionexx.com]
 
Email: [mailto:mgertz@bionexx.com mgertz@bionexx.com]
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<div style="max-width:600px;">
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{{#display_map:
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-18.891951, 47.526831~'''BIONEXX'''<br>Injet Building - 2nd floor~~;
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|type=satellite
 +
|service=google
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|width=auto
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|height=400
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|zoom=16
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|controls=pan, zoom, type, scale
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|copycoords=yes
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|icon=https://www.madacamp.com/images/madagascar/Green_marker.png
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}}
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</div>
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 +
== Further information ==
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* [[Coronavirus Madagascar]]
  
 
__NOTOC__
 
__NOTOC__

Latest revision as of 08:47, 29 December 2020

Madagascar: producing the active ingredient for the world's only WHO approved anti-malaria drug

Malaria kills more than 400,000 people every year. 90% of these people live in Africa and by far the most of them are children under the age of five. According to UNICEF, malaria accounts for about one in six of all childhood deaths in Africa.

Bionexx 010.jpg

In 1971, after reviewing 2,000 candidate recipes, ancient texts, and folk remedies, the Chinese pharmaceutical chemist Tu Youyou discovered the Malaria curing power of a plant named Artemisia annua. It took until 2004 for her invention to enter the market as an approved medicine. Tu received the Nobel Prize in 2015 for her discovery. Today, the so-called Artemisinin Combined Therapies (ACTs) are the only malaria curing medicines that are approved by the World Health Organisation (WHO).

Other medicines exist, but have lost their effectiveness as the virus has developed a resistance against them. The only African country which produces Artemisia annua at a large scale is Madagascar. This is directly linked to the activities of Bionexx. Artemisia annua is typically grown by smallholder farmers. Due to its specific growing and harvesting conditions, it can be cultivated in the low season as a counter-crop of rice.

Bionexx 009.jpg
Bionexx 007.jpg Bionexx 008.jpg Bionexx 012.jpg

For the farmers, Artemisia annua offers a new and interesting type of cash crop. Around 10,000 farmers supply Bionexx in Madagascar and derive about 25% of their annual cash revenue from growing Artemisia annua.

Bionexx Madagascar

Back in 2005, two French entrepreneurs had the view to develop a supply chain to cure malaria on the very continent that is most plagued by this disease: Africa. It took them 10 years of R&D, heavy CAPEX investments, hard work and a lot of perseverance to the point where Bionexx:

  • is a semi-pharmaceutical company active in the identification, development and production of functional ingredients derived from plants, for use in the pharmaceutical, food and personal care industries.
  • had a $ 6.8 million turnover in 2016, of which 80% comes from Artemisinin.
  • has successfully passed the most stringent quality audits of various pharma companies;
  • is now one of the leading Artemisinin suppliers globally, and the only based in Africa;
  • has installed capacity to strongly increase Artemisinin volume in the coming years.

Bionexx 001.jpg
Bionexx 004.jpg Bionexx 005.jpg Bionexx 003.jpg

Strategy

The strategy of Bionexx is based upon:

  • increasing production and sales volume of Artemisinin.
  • increasing the biomass supply through more farmers growing Artemisia annua and to enhance their production per hectare in a sustainable manner.
  • diversification into other products derived on botanical extracts.

Bionexx 011.jpg

Partnerships

Bionexx has several existing partnerships focused on research (e. g. with universities and industrial partners), projects (e. g. local companies and organisations) and the development of activities (local and international companies).

Bionexx is open to discuss new opportunities and partnerships with individuals and organisations interested in the field of curing Malaria.

Bionexx 006.jpg



Short contribution by Martin Gertz (August 2017)

Bionexx was founded 12 years ago with the idea of cultivating the plant Artemisia annua. This was followed in 2007 by the acquisition of an existing factory for plant extraction in Fianarantsoa, the testing of cultivation technology and cooperation with the farmers as well as the expansion of capacities and abilities for the extraction. Now in the second phase, the focus is mainly on the increase of production. We have already made good progress which is reflected in the biomass production (1,500 tons), the number of farmers (about 10,000) and the number of employees (450). There are also a few other projects which have been launched in parallel and partly with partners (e.g. joint ventures for the extraction of quinine from tree bark) and which are supposed to shape the 3rd phase in the development of Bionexx.

As Corporate Finance Manager, one of my tasks is to find more partners. Our focus is on impact-oriented partners who support the approach and the strategic perspective of Bionexx. We are open to cooperation with institutional (funds, foundations) as well as strategic or private investors.

In the future, we will also seek further project or activity related partnerships with local or international companies and institutions.

Please contact me if you are interested or know someone who is interested in a partnership with Bionexx.

Martin Gertz
Corporate Finance Manager

Bionexx S.A.
Tana Waterfront (Injet building, 2nd floor)
Ambodivona
BP 8707
101 - Antananarivo
Madagascar

Website: www.bionexx.com
Tel: +261 (0)32 03 023 21
Email: mgertz@bionexx.com

Loading map...

Further information