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Sambirano is a valley in north west Madagascar producing cocoa cacao beans famous for various brand of premium quality and organically produced Malagasy chocolate.

The name also refers to the Sambirano River which flows from [[Tsaratanana Massif]], the highest peak of the island, and into the Ampasindava Bay, where it joins with the Ramena river, south of [[Ambanja]].

The Sambirano plain is where the river runs towards the sea, which has highly fertile grounds due to a the hot and humid climate, similar to the eastern part of Madgascar, while in general, the west coast of Madagascar is drier.